Structure-based Systems Biology and Chemical Biomedicine Lab

    
Institute of Biological Chemistry

 

 

 

 

 

 

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Selected Publication:

A. Journal Papers

1.      Chun-Hua Hsu, Chinpan Chen*, Maou-Lin Jou, Alan Yueh-Luen Lee, Yu-Ching Lin, Yi-Ping Yu, Wei-Ting Huang and Shih-Hsiung Wu*. Structural and DNA-Binding Studies on the Bovine Antimicrobial Peptide, Indolicidin: Evidence for Multiple Conformations Involved in Binding to Membranes and DNA. Nucleic Acids Res. 2005 Aug;33(13):4053-64. (Featured on Figure) (SCI:7.260) [PubMed]

 2.      Chun-Hua Hsu, Tzu-Ping Ko, Hui-Ming Yu, Tswen-Kei Tang, Shui-Tsung Chen and Andrew H.-J. Wang*. Immunological, Structural and Preliminary X-ray Diffraction Characterizations of the Fusion Core of the SARS-Coronavirus Spike Protein. Biochem. Biophys. Res. Commun. 2004 Nov 12; 324 (2): 761-7. (SCI:2.904, Biophysics 22/66) [PubMed]

3.       Alan Yueh-Luen Lee, Chun-Hua Hsu and Shih-Hsiung Wu*. Functional Domains of Brevibacillus thermoruber Lon Protease for Oligomerization and DNA Binding: Role of N-terminal and sensor and substrate discrimination domains. J Biol Chem. 2004 Aug 13;279(33):34903-12. (SCI:6.355) [PubMed]

4.       Chun-Hua Hsu, You-Di Liao*, Yun-Ru Pan, Lih-Woan Chen, Shih-Hsiung Wu, Ying-Jen Leu and Chinpan Chen*. Solution Structure of the Cytotoxic RNase 4 from Oocytes of Bullfrog Rana catesbeiana. J Mol Biol. 2003 Feb 28;326(4):1189-201. (SCI:5.239) [PubMed]

5.       Chun-Hua Hsu, Shih-Hsiung Wu*, Ding-Kuo Chang and Chinpan Chen*.  Structural Characterizations of Fusion-Peptide Analogs of Influenza Virus Hemagglutinin: Implication of the Necessity of a Helix-Hinge-Helix Motif in Fusion Activity.  J Biol Chem. 2002 Jun 21;277(25):22725-33. (SCI:6.696) [PubMed]

6.      Chinpan Chen*, Chun-Hua Hsu, Ning-Yuan Su, Yu-Ching Lin, Shyh-Horng Chiou* and Shih-Hsiung Wu*. Solution Structure of a Kunitz-Type Chymotrypsin Inhibitor Isolated from the Elapid Snake Bungarus fasciatus. J Biol Chem. 2001 Nov 30;276(48):45079-87. (SCI:7.258) [PubMed]

7.        Chun-Hua Hsu, You-Di Liao, Shih-Hsiung Wu and Chinpan Chen*. 1H, 13C and 15N Resonance Assignments and Secondary Structure of the Cytotoxic Protein RNase 4 from Bullfrog Rana catesbeiana Oocytes. J Biomol NMR. 2001 May;20(1):93-4. (SCI:4.636, Spectroscopy 3/40) [PubMed]

8.         Chun-Hua Hsu, Lih-Woan Chen, You-Di Liao, Shih-Hsiung Wu and Chinpan Chen*. 1H, 15N and 13C Resonance Assignments and Secondary Structure Determination of the RC-RNase 2 from Oocytes of Bullfrog Rana catesbeiana.  J Biomol NMR. 2001 Jan;19(1):87-8. (SCI:4.636, Spectroscopy 3/40) [PubMed]

9.        Chun-Hua Hsu*. Determination of Tertiary Structure of Carbohydrate Molecules. Chemistry (The chinese chem. Soc., Taipei) 2000 Jun; 58(2):323-6.

 

B. Conference Papers

1.     Chun-Hua Hsu, Tzu-Ping Ko, Hui-Ming Yu, Tswen-Kei Tang, Shui-Tsung Chen and Andrew H.-J. Wang. “Structural and Immunological Characterization of the Fusion Core of the SARS-coronavirus Spike Protein” (Aug 23-31, 2005) P-1525, XX Congress of the International Union of Crystallography, Florence, Italy.

2.     Chun-Hua Hsu and Andrew H.-J. Wang. “High-throughput expression of HBV X protein” (Dec 13-17, 2003). The 43th Annual Meeting of American Society for Cell Biology. San Francisco, California, U.S.A.

3.     Chun-Hua Hsu, Jeu-Ming P. Yuann, Andrew H. Wang. “Structure detemination and DNA-binding properties of Sso7C4, a thermostable protein from the archaeon Sulfolobus solfataricus (2003) Fourth East Asian Biophysics Symposium, Taipei, Taiwan, ROC.

4.     Yuan-Chao Lou, Chun-Hua Hsu, Yun-Ru Pan, Yi-Hsuan Ho, Chung-De Chen, You-Di Liao, Chinpan Chen. “Biophysical Characteristics of Cytotoxic Ribonucleases from Rana catesbeiana (2003) Fourth East Asian Biophysics Symposium, Taipei, Taiwan, ROC.

5.     Chinpan Chen, Chun-Hua Hsu, Yun-Ru Pan, Lih-Woan Chen, Shih-Hsiung Wu, You-Di Liao. “Biophysical Studies of Cytotoxic Ribonucleases from Rana Catesbeiana (Aug 25-30,2002) PL354, XXth ICMRBS (International Conference on Magnetic Resonance in Biological Systems), Toronto, Canada.

6.     Chun-Hua Hsu, Shih-Hsiung Wu , Ding-Kwo Chang , Chinpan Chen. “Structural Characterizations of Fusion–Peptide Analogs of Influenza Virus Hemagglutinin: Implication of the Necessity of a Helix-Hinge-Helix Motif in Fusion Activity” (2002) The 8th Biophysical Society Annual Meeting And Frontier Biophysics Symposium, Taiwan, ROC.

7.     Chun-Hua Hsu, Yun-Ru Pan, Lih-Woan Chen, Tung-Liang Lee, You-Di Liao, Shih-siung Wu, Chinpan Chen. “Biophysical Studies of Cytotoxic Ribonucleases from Rana catesbeiana (2002) The 8th Biophysical Society Annual Meeting And Frontier Biophysics Symposium, Taiwan, ROC.

8.     Chun-Hua Hsu, Shih-Hsiung Wu, Chinpan Chen. “The Structural Study of the Fusion Peptide Analogs of Influenza Virus Hemagglutinin Implicates an a-helix is not sufficient for fusion activity.” (2001) The Seventh Symposium on Recent Advances in Biophysics, Taiwan, ROC.

9.     Chun-Hua Hsu, Shih-Hsiung Wu, Shyh-Horng Chiou, Chinpan Chen. “Solution Structure of Bungarus fasciatus IX, a Kunitz-type chymotrypsin inhibitor” (2001) The Seventh Symposium on Recent Advances in Biophysics, Taiwan, ROC.

10.   Chun-Hua Hsu, Ning-Yuan Su, Cindy C-J Kao, Shih-Hsiung Wu, You-Di Liao, Chinpan Chen. “The Solution structures and Structure-Function Studies of Ribonucleases from Rana catesbeiana (bullfrog) which Possess Different Ribonucleolytic Activity and Cytotoxicity.” (May 22-25, 2000) PA-85, Third East Asian Biophysics Symposium, Kyongju, Korea.

11.   Chun-Hua Hsu, Shih-Hsiung Wu, Shyh-Horng Chiou, Chinpan Chen. “Solution Structure of BF9, A Neurotoxin and Protease Inhibitor from the Venom of Bungarus fasciatus.” (2000) Eighth Symposium on Recent Advances in Cellular and Molecular Biology. Taiwan, ROC.

12.   Chun-Hua Hsu, Shih-Hsiung Wu, Shyh-Horng Chiou, Chinpan Chen. “Solution Structure of BF9, a Neurotoxin and Protease Inhibitor from the Venom of Bungarus fasciatus. (1999) The Second Taiwan-Japan Nuclear Magnetic Resonance Symposium (TJNMRS). Taiwan, ROC.

13.   Chun-Hua Hsu, Cindy C-J Kao, Chieh-Min Wang, Yi-Ping Yu, Shih-Hsiung Wu, Chinpan Chen. “Conformations of The Fusion Peptide Analogues of Influenza Virus Hemagglutinin HA2.” (1999) The Second Taiwan-Japan Nuclear Magnetic Resonance Symposium (TJNMRS). Taiwan, ROC.

14.   Chun-Hua Hsu, Chinpan Chen, Shyh-Horng Chiou, Shih-Hsiung Wu. “Solution Structure of BF9, a Neurotoxin and Protease Inhibitor from the Venom of Bungarus fasciatus (1998), 1998 Fall Camp, the society for biochemistry and molecular biology, taipei, Taiwan.

 

 

©2006 Hsu Research Group