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基因體暨生物資訊學研究所 助理教授

Dr. Liu, Jyung-Hurng 劉俊宏 博士

結構生物資訊學實驗室

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研究著作

[English version]

Google Scholar
  1. Hsieh, J.-Y., Li, S.-Y., Chen, M.-C., Yang, P.-C., Chen, H.-Y., Chan, N.-L., Liu, J.-H., Hung, H.-C. (2014, Jul.) Structural characteristics of the nonallosteric human cytosolic malic enzyme. Biochim. Biophys. Acta 1844, 1773-83. doi: 10.1016/j.bbapap.2014.06.019
    (SCI, IF 2013=3.191; Times cited: 0) [PubMed] [BBA] [PDB]
  2. Hsieh, J.-Y., Liu, J.-H., Yang, P.-C., Lin, C.-L., Liu, G.-Y., Hung, H.-C. (2014, Jun.) Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme. PLoS ONE 9, e98385. doi: 10.1371/journal.pone.0098385
    (SCI, IF 2013=3.534; Times cited: 0) [PubMed] [PLoS ONE]
  3. Chepyshko, H., Lai, C.-P., Huang, L.-M., Liu, J.-H., and Shaw, J.-F. (2012, Jul.) Multifunctionality and diversity of GDSL esterase/lipase gene family in rice (Oryza sativa L. japonica) genome: new insights from bioinformatics analysis. BMC Genomics 13, 309. doi: 10.1186/1471-2164-13-309
    (SCI, IF 2013=4.041; Times cited: 9) [PubMed] [BMC Genomics]
  4. Hsieh, J.-Y., Liu, J.-H., Fang, Y.-W., Hung, H.-C. (2009, May.) Dual roles of Lys57 at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme. Biochem. J. 402, 201-9. doi: 10.1042/BJ20090076
    (SCI, IF 2013=4.779; Times cited: 2) [PubMed] [Biochem J]
  5. Li, T.-N., Chin, K.-H., Liu, J.-H., Wang, A H.-J., Chou, S.-H. (2009, May.) XC1028 from Xanthomonas campestris adopts a PilZ domain-like structure without a c-di-GMP switch. Proteins. 75, 282-8. doi: 10.1002/prot.22330
    (SCI, IF 2013=2.921; Times cited: 21) [PubMed] [Proteins] [PDB] [Proteopedia]
  6. Chou,C.-C., Chang, C.-W., Liu, J.-H., Chen, L.-F., Hsiao, C.-D., Chen, H.-W. (2007, Jul.) Small ubiquitin-like modifier modification regulates the DNA binding activity of glial cell missing Drosophila homolog a. J. Biol. Chem. 282, 27239-49. doi: 10.1074/jbc.M700351200
    (SCI, IF 2013=4.600; Times cited: 15) [PubMed] [JBC]
  7. Wang, C.-H.*, Liu, J.-H.*, Lee, S.-C., Wu, W.-g., and Hsiao, C.-D. (2006, Jan.) Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin: the sulfatide/cardiotoxin complex structure in a membrane-like environment suggests a lipid-dependent cell-penetrating mechanism for membrane binding polypeptides. J. Biol. Chem. 281, 656-77. doi: 10.1074/jbc.M507880200
    (SCI, IF 2013=4.600; Times cited: 43)
    *These authors contributed equally to this work. [PubMed] [JBC] [PDB] [Proteopedia]
  8. Liu, J.-H., Chang, T.-W., Huang, C.-Y., Chen, S.-U., Wu, H.-N., Chang, M.-C., Hsiao, C.-D. (2004, Nov.) Crystal structure of PriB, a primosomal DNA replication protein of Escherichia coli. J. Biol. Chem. 279, 50465-71. doi: 10.1074/jbc.M406773200
    (SCI, IF 2013=4.600; Times cited: 29) [PubMed] [JBC] [PDB] [Proteopedia]
  9. Forouhar, F., Huang, W.-N., Liu, J.-H., Chien, K.-Y., Wu, W.-g. and Hsiao, C.-D. (2003, Jun.) Structural basis of the membrane-induced cardiotoxin A3 oligomerization. J. Biol. Chem. 278, 21980-8. doi: 10.1074/jbc.M208650200
    (SCI, IF 2013=4.600; Times cited: 57) [PubMed] [JBC] [PDB] [Proteopedia]
  10. Liu, J. H., Liao, Y. D., Sun Y. J. (2001, Nov.) Crystallization and preliminary X-ray diffraction analysis of cytotoxic ribonucleases from bullfrog Rana catesbeiana. Acta Crystallogr. D57, 1697-9. doi: 10.1107/S0907444901013191
    (SCI, IF 2013=7.232; Times cited: 1) [PubMed] [Acta Cryst.]

研討會壁報

  1. Li, J.-Y., Chen, C. K.-M., Chang, S.-W., Shaw, J.-F., Wang, A. H.-J., and Liu, J.-H. (2012, Oct.) Preliminary X-ray crystallographic analysis of trehalose synthase from Deinococcus radiodurans. The 18th NSRRC Users' Meeting.
  2. Chen, J.-W., Nien, C.-Y., Chen, C. K.-M., Chang, S.-W., Shaw, J.-F., Wang, A. H.-J., and Liu, J.-H. (2012, Oct.) Preliminary X-ray crystallographic analysis of trehalose synthase from Picrophilus torridus. The 18th NSRRC Users' Meeting.
  3. Nien, C.-Y., Cheng, C.-Y., Liu, J.-H., Shaw, J.-F., and Chen, Y.-T. (2012, May.) Crystal structure of glutaredoxin from Chlorella sorokiniana T-89. The 17th Biophysics Conference.
  4. Hung, S.-J. and Liu, J.-H. (2012, May.) Design of an accurate predictor for the thermostable protein design in PERT server. The 17th Biophysics Conference.
  5. Wu, J.-E., Chiu, S.-W., Yang, J.-Y., and Liu, J.-H. (2012, Mar.) Crystal structure of XopAI from Xanthomonas axonopodis pv. citri. 2012 International Conference on c-di-GMP and Xanthomonads.
  6. Hung, S.-J. and Liu, J.-H. (2011, Dec.) PERT: an integrated informatics platform for thermostable protein design. 2011 Taiwan Enzyme Mechanism Conference.
  7. Nien, C.-Y., Cheng, C.-Y., Shaw, J.-F., Chen, Y.-T., and Liu, J.-H. (2011, Oct.) Crystallization and preliminary X-ray crystallographic analysis of Chlorella glutaredoxin. The 17th NSRRC Users' Meeting.
  8. Wu, J.-E., Chiu, S.-W., Yang, J.-Y., and Liu, J.-H. (2010, Oct.) Crystallization and preliminary X-ray crystallographic analysis of XopAI from Xanthomonas axonopodis pv. citri. The 16th NSRRC Users' Meeting.
  9. Liu, J.-H., Hong, C.-S., Chang, S.-W., and Shaw, J.-F. (2009, Nov.) Investigation of the structural basis for thermostability of trehalose synthase from Picrophilus torridus. The 5th International Symposium on Biocatalysis and Biotechnology.
  10. Hsu, Y.-J. and Liu, J.-H. (2009, Oct.) Effects of trimethylamine-N-oxide (TMAO) on the interactions of lysozyme in crystal. The 15th NSRRC Users' Meeting.